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Autism and Stem Cells

Dr Chun Wong writes that everyone has heard of stem cell research and how some scientists believe that stem cells can be used to treat, cure or fix certain diseases and conditions like cancer and cerebral palsy, but now stem cell therapy is also being linked to developmental disorders like autism.

Well, scientists like Dr Leonard Smith (a gastrointestinal, vascular and general surgeon) and his team of researchers believe that autism is characterized by:-
* Hypoperfusion - A reduction in the amount of oxygen supplied to the brain. A reduced oxygen supply causes damage to the tissue of the brain and means that the brain can no longer function properly.
* Immune Dysregulation - Abnormal immune responses. The child’s immune system does not function properly and does not respond appropriately to the stimulation it receives. Children with autism can suffer with autoimmune responses, chronic inflammation in the brain and gut (leading to all manner of gastrointestinal problems) and suppressed immune systems.

Dr Smith and his colleagues have identified two types of stem cells which they believe are effective in addressing these two characteristics of autism:-

1. CD34+ cord blood stem cells - Dr Smith’s colleague Dr Fabio Solano injected this type of stem cell into a patient to improve blood flow to the brain and therefore increasing the brain’s oxyegn supply.
2. Mesenchymal stem cells (MSC) - This stem cell has been used in the past to treat immune dysregulation in Crohn’s Disease sufferers and was used by the research team to treat inflammation in autistic children.

You can read their research and findings at http://www.translational-medicine.com/content/5/1/30#IDABE20Y

Watch the youtube to see how a little girl’s autism was successfully treated by adult stem cells given to her by Dr Fabio Solano.

But is stem cell therapy a cure for autism and is it even a viable treatment?
Other articles and science reports on Adult Stem Cells.
Check, E., Cardiologists take heart from stem-cell treatment success, Nature 428(6986):880, 29 April 2004: "Adult stem cells have long been viewed as less flexible than embryonic stem cells, which can divide to produce any cell type in the body. But recent studies of human cells suggest that adult stem cells can also turn into many cell types, including heart, brain and liver cells."

Terada, N. et al., Bone marrow cells adopt the phenotype of other cells by spontaneous cells fusion, Nature (416(6880):542–545, 4 April 2002.

Cohen, P., Stem cells could save sight, New Scientist 175:(2354):18, 3 August 2002.

Stem cells do their stuff for Parkinson’s patient, New Scientist 174(2338):5, 13 April 2002.

Randerson, J., Stem cells fix the damage, New Scientist 177(2377):14, 11 January 2003.

Pluchino, S. et al., Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis, Nature 422(6933):688–694, 17 April 2003.

Jochen Ringe et al., Stem cells for regenerative medicine: advances in the engineering of tissues and organs, Naturwissenschaften 89(8), August 2002.

About the Formulator of StemEnhance - Christian Drapeau
Mr. Drapeau, a foremost scientist in the study of Aphanizomenon flos-aquae, holds a Masters of Science degree in Neurology and Neurosurgery from the Montreal Neurological Institute, an affiliate of McGill University in Montreal, Quebec, Canada. He has been extensively involved in the study of nutrition, naturopathy, and various natural therapies.

Most significantly, Mr. Drapeau collaborated with many scientists affiliated with Harvard University, McGill University, the University of Illinois, Oregon State University, the University of New Mexico, and the University of Mississippi in the study of the effects of blue-green algae (Aphanizomenon flos-aquae) on human health. Mr. Drapeau continues his involvement in the clinical study of AFA.

Circulating stem cells can reach various organs and become cells of that organ, helping such organ regain and maintain optimal health. Recent studies have suggested that the number of circulating stem cells is a key factor; the higher the number of circulating stem cells the greater is the ability of the body at healing itself. What happens to stem cells if they do not reach a tissue? Stem cells released from the bone marrow that do not reach a tissue simply return to the bone marrow after some time

United States Patent Patent No.: 6,814,961 B1 Date of Patent: November 9, 2004 Subj: METHOD FOR ENHANCING STEM CELL PHYSIOLOGY Inventors: Gitte S. Jensen and Christian Drapeau