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Adult Stem Cell Research Study Provides Hope for Kidney, Liver Patients

by Steven Ertelt
LifeNews.com Editor
September 6, 2006


Florence, Italy (LifeNews.com) -- Italian scientists have made advances in adult stem cell research that may provide new hope for patients suffering from liver or kidney diseases. The research team has identified kidney stem cells that helped kidneys repair themselves and the discovery could lead to new treatments.
A team led by top immunologist Sergio Romagnani said the new kidney cells appear to be able to turn into an array of other cells in the body.

"Chronic renal diseases and terminal renal insufficiency are viewed as the medical emergency of the new century," Romagnani told a press conference, according to the ANSA Italian news agency.

He said the team found that the adult stem cells repaired kidney damage in the mice used in the study. That's important because current treatments merely slow the disease but don't repair damage it causes.

"This is particularly important because the drugs we currently have are only able to slow down kidney damage," he said, according to the ANSA report.

Because the cells can differentiate into bone cells, adipose (fatty tissue) cells and even nerve cells there is hope of helping to reverse degenerative diseases in those areas as well, he explained.

The team published the results of their new studies in the Journal of the American Society of Nephrology.

Meanwhile, one day after Romagnani's press conference, a team in Turin announced, in the latest edition of the journal Stem Cells, that the adult kidney cells are able to become pluripotent.

"The progenitor cells identified by our team are able to differentiate into liver cells, bone cells, blood cells and even pancreatic cells that produce insulin," lead researcher Benedetta Bussolati told ANSA.

"The diffentiating capacity of these cells holds promise that they can be used in regenerative medicine such as cell therapy, an alternative to the use of embryonic stem cells," she said.

The studies show another alternative to embryonic stem cell research, which involves the destruction of human life.
Other articles and science reports on Adult Stem Cells.
Check, E., Cardiologists take heart from stem-cell treatment success, Nature 428(6986):880, 29 April 2004: "Adult stem cells have long been viewed as less flexible than embryonic stem cells, which can divide to produce any cell type in the body. But recent studies of human cells suggest that adult stem cells can also turn into many cell types, including heart, brain and liver cells."

Terada, N. et al., Bone marrow cells adopt the phenotype of other cells by spontaneous cells fusion, Nature (416(6880):542–545, 4 April 2002.

Cohen, P., Stem cells could save sight, New Scientist 175:(2354):18, 3 August 2002.

Stem cells do their stuff for Parkinson’s patient, New Scientist 174(2338):5, 13 April 2002.

Randerson, J., Stem cells fix the damage, New Scientist 177(2377):14, 11 January 2003.

Pluchino, S. et al., Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis, Nature 422(6933):688–694, 17 April 2003.

Jochen Ringe et al., Stem cells for regenerative medicine: advances in the engineering of tissues and organs, Naturwissenschaften 89(8), August 2002.

About the Formulator of StemEnhance - Christian Drapeau
Mr. Drapeau, a foremost scientist in the study of Aphanizomenon flos-aquae, holds a Masters of Science degree in Neurology and Neurosurgery from the Montreal Neurological Institute, an affiliate of McGill University in Montreal, Quebec, Canada. He has been extensively involved in the study of nutrition, naturopathy, and various natural therapies.

Most significantly, Mr. Drapeau collaborated with many scientists affiliated with Harvard University, McGill University, the University of Illinois, Oregon State University, the University of New Mexico, and the University of Mississippi in the study of the effects of blue-green algae (Aphanizomenon flos-aquae) on human health. Mr. Drapeau continues his involvement in the clinical study of AFA.

Circulating stem cells can reach various organs and become cells of that organ, helping such organ regain and maintain optimal health. Recent studies have suggested that the number of circulating stem cells is a key factor; the higher the number of circulating stem cells the greater is the ability of the body at healing itself. What happens to stem cells if they do not reach a tissue? Stem cells released from the bone marrow that do not reach a tissue simply return to the bone marrow after some time

United States Patent Patent No.: 6,814,961 B1 Date of Patent: November 9, 2004 Subj: METHOD FOR ENHANCING STEM CELL PHYSIOLOGY Inventors: Gitte S. Jensen and Christian Drapeau